Sphingosine-1 kinase (SphK1)

鞘甘氨酸-1 激酶

英文解释

Sphingosine-1 kinase (SphK1) is one of two sphingosine kinases that phosphorylate sphingosine into sphingosine-1-phosphate (S1P). S1P is generally exerts pro-inflammatory, pro-angiogenic, immunomodulatory, and pro-survival activity.

中文解释

鞘甘氨酸-1 激酶 (SphK1) 是一种鞘甘氨酸激酶，可将鞘甘氨酸磷酸化为鞘甘氨酸-1-磷酸 (S1P)。S1P通常具有促炎、促血管生成、免疫调节和促生存活性。

参考文献

[1]. Bonica J, et al. Transcriptional Regulation of Sphingosine Kinase 1. Cells. 2020 Nov 8;9(11):2437.