Cy5.5 azide (non-sulfonated)

used for Click chemistry to label alkyne-modified oligonucleotides

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库存: 现货

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价格

促销价

数量
5mg

￥3800.00

3040.00

- +
25mg

￥12387.00

9910.00

- +

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货号: ajcx11288
CAS: N/A
别名:
分子式: C43H49ClN6O
分子量: 701.34
纯度: >98%
溶解度: ≥ 70.1mg/mL in DMSO, ≥ 46.2 mg/mL in EtOH with ultrasonic
储存: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
库存: 现货

Background

This Cy5.5 is a labeling reagent that ready for the use in Click Chemistry reaction which available as 10 mM solution in DMSO. As Cy5.5 azide is a far-red emitting dye, it can replace Alexa Fluor 680, and DyLight 680. Most derivatives of non-sulfonated cyanines have low aqueous solubility except for hydrochlorides of hydrazides and amines. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer.

In human glioblastoma U87MG cells, to assess the capability of the Cu(I)/M-dots for cell labeling Cy5.5-azide was in combination with Cu(I)/M-dots for imaging of the integrin αⅤβ3 receptor [1].

Reference:
[1] Sun, Y.?; Hong, S.; Ma, X.; Cheng, K.; Wang, J.; Zhang, Z.; Yang, M.; Jiang, Y.; Hong, X.; Cheng, Z. Recyclable Cu(I)/Melanin Dots for Cycloadditions, Bioconjugation and Cell Labeling. Chemical Science.