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Monepantel (AAD1566)
Monepantel (AAD1566) 是一种有机驱虫药,可作为烟碱乙酰胆碱受体 (nAChR) 亚基的线虫特异性进化枝的正变构调节剂。
Lubiprostone
A ClC-2 activator
PTC124(Ataluren)
Selective inducer of stop codon read-through
(S)-nitro-Blebbistatin
A more stable form of (–)-blebbistatin
(-)-(S)-B-973B
(-)-(S)-B-973B为一种有效的α7nAChR别构激动剂和正别构调节剂,具有镇痛作用。
MQAE
A fluorescent chloride indicator dye
Fluxametamide
Fluxametamide是一种广谱的杀虫剂,为GABA-和谷氨酸门控氯离子通道(chloridechannel)拮抗剂,对M.domestica中GABACl和GluCl的IC50值分别为1.95?nM和225?nM。
GLPG1837(ABBV-974)
A CFTR potentiator
Nisoldipine
A calcium channel inhibitor
TMB 8 (hydrochloride)
A non-competitive antagonist of nAChRs and an inhibitor of intracellular calcium availability
Transdermal Peptide (TD 1 (peptide))
Transdermal Peptide(TD 1(肽))由11个氨基酸组成,是第一个通过噬菌体展示发现的透皮增强肽。
Hellebrin
An Na+/K+-ATPase inhibitor
VX-661
An investigational compound that promotes the maturation of delta F508 CFTR
(S)-3'-amino Blebbistatin
Mivacurium (chloride)
An antagonist of nAChRs and muscarinic M2 and M3 receptors