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Methylprednisolone Sodium Succinate(6α-Methylprednisolone 21-hemisuccinate Sodium)
Methylprednisolone Sodium Succinate是一种糖皮质激素,是一种具有抗炎作用的免疫抑制剂。
PF06650833
PF06650833 (PF-06650833) 是一种有效的、选择性的和口服活性的白细胞介素 1 受体相关激酶 4 (IRAK4) 抑制剂,在细胞和 PBMC 试验中的 IC50 分别为 0.2 和 2.4 nM。
Arginase inhibitor 1
An arginase inhibitor
Durvalumab
Durvalumab (anti-PD-L1) is a selective, high affinity human IgG1 mAb that blocks programmed cell death ligand-1 (PD-L1) binding to PD-1 (IC50=0.1 nM) and CD80 (IC50=0.04 nM). MW=146.3 kDa.
CB-1158 (INCB01158)
Nivolumab (BMS-936558)
Nivolumab (BMS-936558) 是一种程序性死亡受体-1 (PD-1) 阻断人 IgG4 抗体,用于治疗晚期(转移性)非小细胞肺癌。
JHU-083
JHU-083 (Ethyl 2-(2-Amino-4-methylpentanamido)-DON) is a novel prodrug of DON.JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress.Solutions are best fre
C3a Receptor Agonist
A C3a receptor agonist
MCC950 (CP-456773)
An inhibitor of NLRP3 inflammasome activation
Furimazine (PBI 3939)
Furimazine是一种咪唑并吡嗪酮类的发光底物。在哺乳动物细胞中,NanoLuc(Nluc)与Furimazine联用,产生更亮的发光,比带Coelenterazine的Oluc-19高250万倍。
SU5416
A tyrosine kinase inhibitor
PP121
A potent dual inhibitor of tyrosine and phosphoinositide kinases
FICZ
FICZ (Formyl-indolo [3,2-b] carbazole), as an endogenous ligand for the aryl hydrocarbon receptor (AhR).
β-Zearalenol
A hepatic metabolite of zearalenone
PD-1-IN-1 (CA-170)
PD-1-IN-1 (CA-170) 是一种口服给药的 VISTA 和 PD-L1 双重抑制剂。