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Romidepsin (FK228, depsipeptide)
Benzenebutyric acid (4-Phenylbutyric acid,4-苯基丁酸)
ACY-241
An HDAC6 inhibitor
7,4'-Dihydroxyflavone
Valproic acid
A class I HDAC inhibitor
CBHA
Inhibitor of histone deacetylases
Entinostat (MS-275,SNDX-275)
A histone deacetylase inhibitor
Trapoxin A
Trapoxin A is a cyclotetrapeptide histone deacetylase (HDAC) inhibitor.
2-hexyl-4-Pentynoic Acid
An HDAC inhibitor
PCI-34051
A potent, selective HDAC8 inhibitor
HPOB
A potent and selective inhibitor of HDAC6
EDO-S101
An HDAC inhibitor and DNA alkylating agent
SAHA-BPyne
A probe for HDAC activity
Nanatinostat
Nanatinostat (CHR-3996) 是一种有效的,有口服活性、I 类选择性的组蛋白去乙酰化酶 (HDAC) 抑制剂,IC50 值为 8 nM。
Tefinostat
Tefinostat (CHR-2845) 是一种单核细胞/巨噬细胞靶向的 HDAC 广谱抑制剂,通过细胞内酯酶人羧酸酯酶-1 (hCE-1) 切割成活性酸 CHR-2847。具有抗抗单核细胞系白血病活性。