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Miltefosine
An inhibitor of CCT
K-80003 (TX-803)
Recilisib (Ex-RAD)
Recilisib (Ex-RAD) (ON 01210) 是一种辐射防护剂,可激活细胞中的 AKT、PI3K 活性。
GSK2110183
Afuresertib (GSK2110183) is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.
Crebanine
An aporphine alkaloid with diverse biological activities
AKT-IN-1
AKT-IN-1是一种变构AKT抑制剂,IC50为1.042μM。
PF-AKT400 (AKT protein kinase inhibitor)
PF-AKT400(AKT 蛋白激酶抑制剂)是一种广泛选择性、强效、ATP 竞争性 Akt 抑制剂,对 PKBα 的选择性高出 900 倍; (IC50=0.5 nM) 比 PKA (IC50=450 nM)。
Ipatasertib dihydrochloride (GDC-0068 (dihydrochloride))
A pan-Akt inhibitor
Crosstide
A peptide substrate for Akt
MK-2206 dihydrochloride
Akt1 and Akt2-IN-1
Akt1andAkt2-IN-1是一种有效的变构抑制剂,抑制Akt1(IC50=3.5nM)和Akt2(IC50=42nM)。
Uprosertib hydrochloride
A selective Akt inhibitor
AKT inhibitor VIII
A potent inhibitor of Akt1 and Akt2
Loureirin A
Loureirin A is a flavonoid extracted from the red resin of the herbs of Dracaena cochinchinensis, which is known as Dragon's Blood. Loureirin A inhibits platelet activation by an impairment of PI3K/Akt signaling. Loureirin A inhibits Akt phosphorylation.
GSK2110183 hydrochloride
GSK2110183 hydrochloride 是 GSK2110183 的结构类似物。