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MBX-4132,一种称为恶二唑的化学类别的成员,通过与细菌核糖体结合来抑制反式翻译。
MBX-4132, a member of a chemical class called oxadiazoles that inhibit trans translation by binding to the bacterial ribosome.
MBX-4132, which interferes with protein synthesis by blocking trans translation, has several characteristics that could make it a match for Neisseria gonorrhoeae (N. gonorrhoeae)[1].
参考文献:
[1]. Anette Breindl, et al. Ribosome allows for multiple shots on giant goal.
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