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Mito-TRFS 是第一个关闭式探针,用于对活细胞中的线粒体硫氧还蛋白还原酶 (TrxR2) 进行成像。
Mito-TRFS is the first off-on probe for imaging the mitochondrial thioredoxin reductase (TrxR2) in live cells.
Reference:
[1]: Liu Y, Ma H, Zhang L, Cui Y, Liu X, Fang J. A small molecule probe reveals declined mitochondrial thioredoxin reductase activity in a Parkinson's disease model. Chem Commun (Camb). 2016 Feb 7;52(11):2296-9. doi: 10.1039/c5cc09998f. PubMed PMID: 26725656.
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