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An anticancer phytochemical
Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica?L). Nimbolide induces apoptosis through inactivation of?NF-κB. Nimbolide inhibits?CDK4/CDK6?kinase activity. Nimbolide suppresses the NF-κB, Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways[1]
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