A prodrug form of SGC8158
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SGC3027 is a?histone methyltransferase?inhibitor[1]. SGC3027 is the first potent, selective and cell active chemical probe for?PRMT7[2]
SGC3027 is a pro-drug of SGC8158 which releases the active component upon reduction in the cell by reductases. In cellular assays using C2C12 cells, SGC3027 inhibits the methylation of HSP70 with IC50=1.3 μM[2].