(R)-UT-155
(R)-UT-155(compound11)是一种选择性的、雄激素受体降解物(SARD)配体。活性低于S型异构体。
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- 货号: ajcx12452
- CAS: 2031161-54-1
- 别名:
- 分子式: C20H15F4N3O2
- 分子量: 405.35
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
(R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. Less active than the S-isomer[1][2].
[1]. US20180360805. [2]. Ponnusamy S, et al. Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer. Cancer Res. 2017 Nov 15;77(22):6282-6298.
