TMP778
TMP778 is a selective inhibitor of RORγt with an IC50 of 5 nM in the Fluorescence Resonance Energy Transfer (FRET) assay and an IC50 of 17 nM in the RORγ assay.
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250mg￥0.000.00- +
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500mg￥0.000.00- +
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- 货号: ajcx12516
- CAS: 1422171-08-1
- 别名:
- 分子式: C31H30N2O4
- 分子量: 494.58
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
TMP778 is a selective inhibitor of RORγt with an IC50 of 5 nM in the Fluorescence Resonance Energy Transfer (FRET) assay and an IC50 of 17 nM in the RORγ assay.
[1] Cancan Lyu, et al. Eur J Immunol. 2018 Nov;48(11):1810-1816. [2] Sheng Xiao, et al. Immunity. 2014 Apr 17;40(4):477-89.
