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PTP1B-IN-3是有效的,有选择性的PTP1B抑制剂。IC50值为120nM(PTP1B)和120nM(TCPTP)。
PTP1B-IN-3 is a potent and selective PTP1B inhibitor with IC50s of 120 nM (PTP1B) and 120 nM (TCPTP), respectively.
[1]. Patel D, .Discovery of orally active, potent, and selective benzotriazole-based PTP1B inhibitors. ChemMedChem. 2011 Jun 6; 6(6):1011-6.
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