Taniborbactam
Taniborbactam是一种有效的β-lactamase抑制剂，对β-lactamase不同亚型SHV-5，KPC-2，VIM-2和AmpC的IC50值<100nM，对OXA-1的IC50值为0.1-1μM，可用于细菌感染的研究。
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250mg￥0.000.00- +
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500mg￥0.000.00- +
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- 货号: ajcx12790
- CAS: 1613267-49-4
- 别名: VNRX-5133
- 分子式: C19H28BN3O5
- 分子量: 389.25
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
Taniborbactam is a potent inhibitor of β-lactamase, with IC50s of <100 nM for SHV-5, KPC-2, VIM-2, and AmpC β-lactamase, and 0.1 to 1 μM for OXA-1 β-lactamase, used in the research of bacterial infections[1].
Taniborbactam (Example 15) is a potent inhibitor of β-lactamase, with IC50s of <100 nM for SHV-5, KPC-2, VIM-2, and AmpC β-lactamase, and 0.1 to 1 μM for OXA-1 β-lactamase, used in the research of bacterial infections[1].
[1]. Christopher J. Burns, et al. Beta-lactamase inhibitors. WO2014089365A1
