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FR 167653 (FR 167653硫酸盐) (FR 167653 (FR 167653硫酸盐)),一种具有口服活性和选择性的p38 MAPK抑制剂,是TNF-α的强效抑制剂;和 IL-1β;通过特异性抑制 p38 MAPK 活性产生。
FR-167653 is a selective p38 MAPK inhibitor.
[1]. Hattori S, et al. FR-167653, a selective p38 MAPK inhibitor, exerts salutary effect on liver cirrhosis through downregulation of Runx2.
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