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- Checkpoint Kinase (Chk)
- CHK1-IN-2
CHK1-IN-2
CHK1-IN-2是细胞周期检测点激酶(CHK1)的抑制剂，其IC50为6nM。
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- 货号: ajcx12970
- CAS: 912367-45-4
- 别名:
- 分子式: C20H22N4OS
- 分子量: 366.48
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM.
CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM, which is a potential cancer therapeutic that can be utilized for enhancing the efficacy of DNA damaging agents[1].
[1]. Yang B, et al. Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) Inhibitors. J Med Chem. 2018 Feb 8;61(3):1061-1073.
