Target Protein-binding moiety 8|910297-51-7|安捷凯

Target Protein-binding moiety 8

Target Protein-binding moiety 8 (N-Deshydroxyethyl BMS-354825) 是 Dasatinib 的代谢物，Dasatinib 是一种多激酶抑制剂，可有效抑制 Bcr-Abl、Src 家族和血小板衍生的生长因子受体激酶。

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Background

Target Protein-binding moiety 8 is a compound binding to BCR-ABL, and used for inhibiting BCR-ABL activity.

Target Protein-binding moiety 8 (Compound 8) is a compound binding to BCR-ABL, and used for inhibiting BCR-ABL activity.

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

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Target Protein-binding moiety 8

Target Protein-binding moiety 8详情

Background

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