Solenopsin是一种ATP-竞争型AKT抑制剂,withIC50值为10μM.
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Solenopsin is an ATP-competitive AKT inhibitor with IC50 value of 10 μM .
[1]. Arbiser JL, et al. Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis. Blood. 2007 Jan 15;109(2):560-5. Epub 2006 Sep 21.