KRAS G12C inhibitor 5
KRASG12Cinhibitor5是一种KRasG12C抑制剂，详细信息请参考专利文献WO2017201161A1中的化合物147。
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250mg￥0.000.00- +
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500mg￥0.000.00- +
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- 货号: ajcx13124
- CAS: 2158297-63-1
- 别名:
- 分子式: C32H37N7O2
- 分子量: 551.68
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147[1].
Kirsten Rat Sarcoma 2 Viral Oncogene Homolog (KRas) is a small GTPase and a member of the Ras family of oncogenes. KRas serves a molecular switch cycling between inactive (GDP -bound) and active (GTP -bound) states to transduce upstream cellular signals received from multiple tyrosine kinases to downstream effectors to regulate a wide variety of processes, including cellular proliferation[1].
[1]. John P. Fischer, et al. Kras g12c inhibitors. WO2017201161A1.
