Laurolitsinehydrochloride是从台湾雅楠中分离到的生物碱类化合物，具有轻微的抗炎功效。
Laurolitsine hydrochloride is an alkaloid isolated from Phoebe formosana, and shows weak anti-inflammatory activity.
Laurolitsine shows weak anti-inflammatory activity against NO production in RAW 267.4 and BV-2 cells[1]. Boldine, laurolitsine and litebamine (300 μM) remarkedly inhibit the aggregation of rabbit platelets induced by arachidonic acid (100 μM) and collagen (10 μM/mL), and slightly inhibit that induced by ADP (20 μM)[2].
[1]. Zhang SY, et al. [Alkaloids from roots and stems of Litsea cubeba]. Zhongguo Zhong Yao Za Zhi. 2014 Oct;39(20):3964-8. [2]. Teng CM, et al. Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man. J Pharm Pharmacol. 1997 Jul;49(7):706-11.
动态评分
0.0