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Nonapeptide-1acetatesalt是一种多肽激素,是强效的α-黑色素细胞刺激激素(α-MSH)的拮抗剂,其IC50值为11nM。减少黑色素的合成,在很大程度上帮助减少皮肤色素沉着。
Nonapeptide-1 acetate salt, a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM. Reduces synthesis of melanin and helps decrease skin pigmentation to a substantial degree[1].
[1]. Jayawickreme CK, et al. Discovery and structure-function analysis of alpha-melanocyte-stimulating hormone antagonists. J Biol Chem. 1994 Nov 25;269(47):29846-54.
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