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- E3 Ligase Ligand-Linker Conjugate
- E3 ligase Ligand-Linker Conjugates 30 TFA
E3 ligase Ligand-Linker Conjugates 30 TFA
E3 ligase Ligand-Linker Conjugates 30 TFA 包含用于 E3 泛素连接酶 cereblon (CRBN) 配体和 linker。E3 ligase Ligand-Linker Conjugates 30 TFA 可通过 PROTAC 技术合成降解剂。
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包装价格促销价数量
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100mg￥3775.003020.00- +
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500mg￥14425.0011540.00- +
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1g￥26712.0021370.00- +
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2g￥37400.0029920.00- +
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5g￥0.000.00- +
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10g￥0.000.00- +
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- 货号: ajcx13864
- CAS: N/A
- 别名:
- 分子式: C23H29F3N4O9
- 分子量: 562.49
- 纯度: ＞98%
- 溶解度: DMSO: 100 mg/mL (177.78 mM); Ethanol: 100 mg/mL (177.78 mM); Water: 16.67 mg/mL (29.64 mM)
- 储存: Store at -20°C
- 库存: 现货
Background
E3 ligase Ligand-Linker Conjugates 30 TFA incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 30 TFA can be used to design PROTAC degrader[1]. Cereblon
[1]. Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.
