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  • ML204 hydrochloride
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ML204 hydrochloride

A selective TRPC4 channel blocker

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ML204 hydrochloride的二维码
  • 库存: 现货
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  • 包装
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    促销价
    数量
  • 5mg
    ¥837.00
    670.00
    - +
  • 50mg
    ¥4525.00
    3620.00
    - +
  • 100mg
    ¥6687.00
    5350.00
    - +
  • 200mg
    ¥0.00
    0.00
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  • 500mg
    ¥0.00
    0.00
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已选 0 0
金额: ¥0.00
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  • 货号: ajcx14008
  • CAS: 2070015-10-8
  • 别名:
  • 分子式: C15H19ClN2
  • 分子量: 262.78
  • 纯度: >98%
  • 溶解度: Water: ≥ 30 mg/mL (114.16 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

ML-204 selectively blocks transient receptor potential canonical 4 (TRPC4) channels (IC50s = 0.96 and 2.6 μM in fluorescent and electrophysiological assays, respectively).1 It exhibits 19-fold selectivity against TRPC6 and 9-fold selectivity against TRPC5 and does not affect TRPV1, TRPV3, TRPA1, or TRPM8 channels at concentrations up to 22 μM.1


1.Michishita, E., McCord, R.A., Berber, E., et al.SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatinNature452492-496(2008)

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