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Murepavadin (TFA) 是一种14氨基酸环肽,是一种强效、特异性的抗生素,可用于治疗Pseudomonas aeruginosa 引起的细菌感染。Murepavadin (TFA) 靶向作用于脂多糖转运蛋白portin D。
Murepavadin (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic for the treatment of bacterial infections caused by Pseudomonas aeruginosa. Murepavadin (TFA) targets the lipopolysaccharide transport portin D [1]. P. aeruginosa[1].
[1]. Matteo Bassetti, et al. New antibiotics for ventilator-associated pneumonia. Curr Opin Infect Dis. 2018 Jan 13.
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