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ST8154AA1 是抗体偶联药物 ADCs 的一部分,带有 HDAC 抑制剂负荷及连接物,具有抗肿瘤活性。
ST8154AA1 is a part of antibody drug conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity[1].
[1]. Cini E, et al. Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation. Chem Sci. 2018 Jul 3;9(31):6490-6496.
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