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  • 2-Methyl-5-HT
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2-Methyl-5-HT

2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) 是一种有效的选择性 5-HT3 受体激动剂。2-Methyl-5-HT 显示出抗抑郁样作用。

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2-Methyl-5-HT的二维码
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  • 货号: ajcx14328
  • CAS: 78263-90-8
  • 别名: 2-甲基-5-羟基色氨酸盐酸,2-Methyl-5-hydroxytryptamine; 2-Methylserotonin; 2-Me-5-HT
  • 分子式: C11H14N2O
  • 分子量: 190.24
  • 纯度: >98%
  • 溶解度: DMSO: 125 mg/mL (657.06 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects[1].


2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) significantly decreases time of immobility thus showing anti-depressive-like effects[1]. Animal Model: Male Sprague-Dawley rats[1]


[1]. Sumaya IC, et al. Differential effects of a short-term high-fat diet in an animal model of depression in rats treated with the 5-HT3 receptor antagonist, ondansetron, the 5-HT3 receptor agonist, 2-methyl-5-HT, and the SSRI, fluoxetine. Pharmacol Biochem Behav. 2016 May;144:78-84.

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