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Hastatoside 是一种从 Verbena officinalis 中分离出的环烯醚萜苷,具有促进睡眠的作用。
Hastatoside is an iridoid glycoside that is isolated from Verbena officinalis and has a role in promoting sleep[1].
Hastatoside (0.32-0.64 mmol/kg; oral administration; for 9 hours; male rats of the Sprague-Dawley strain) treatment increases the total time of non-rapid eye movement sleep during a 9-h period, with a lag time of about 3-5 h after the administration at 20. 00 hours (lights-off time). Hastatoside also increases the delta activity during non-rapid eye movement sleep[1]. Animal Model: Male rats of the Sprague-Dawley strain (8 weeks old; 260-280 g)[1]
[1]. uki MAKINO, et al. Hastatoside and verbenalin are sleep-promoting
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