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  • Epertinib hydrochloride
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Epertinib hydrochloride

Epertinib hydrochloride (S-222611 hydrochloride) is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4 with IC50 of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib hydrochloride (S-222611 hydrochlorid

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0-14280
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  • 货号: ajcx14664
  • CAS: 2071195-74-7
  • 别名: S-22611 hydrochloride
  • 分子式: C30H28Cl2FN5O3
  • 分子量: 596.48
  • 纯度: >98%
  • 溶解度: DMSO: 125 mg/mL (209.56 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Epertinib hydrochloride (S-222611 hydrochloride) is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4 with IC50 of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib hydrochloride (S-222611 hydrochloride) exhibits antitumor activity.


[1] Hidekazu Tanaka, et al. Cancer Sci. 2014 Aug;105(8):1040-8.

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