MMAF sodium

An auristatin with anticancer activity

原价

￥875-3662

价格

￥ 700-2930

所有产品仅用于科学研究，我们不为任何个人用途提供产品和服务

询价有惊喜，量大更优惠

库存: 现货

可选包装 >>>

首页

产品引用

货号: ajcx14748
CAS: 1799706-65-2
别名: Monomethylauristatin F sodium
分子式: C39H64N5NaO8
分子量: 753.94
纯度: >98%
溶解度: DMSO: ≥ 200 mg/mL (265.27 mM)
储存: Store at -20°C,unstable in solution, ready to use.
库存: 现货

Background

MMAF is an auristatin with anticancer activity.¹ It is cytotoxic to Karpas 299 anaplastic large cell lymphoma, H3396 breast carcinoma, and 786-O and Caki-1 renal carcinoma cells in vitro (IC₅₀s = 119, 105, 257, and 200 nM, respectively), as well as in a panel of 11 lymphoma cell lines (IC₅₀s = 34.8-164 nM).

1.Doronina, S.O., Mendelsohn, B.A., Bovee, T.D., et al.Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: Effects of linker technology on efficacy and toxicityBiconjug. Chem.17(1)114-124(2006)

动态评分

0.0

没有评分数据

没有评价数据

信号通路

生命科学

有机化学

无机化学

材料科学

MMAF sodium

MMAF sodium详情

Background