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MC-VC-PABC-Aur0101 是抗体-药物偶联物的一部分。由微管抑制剂 Aur0101 和 ADC linker MC-VC-PABC 连接而成。
MC-VC-PABC-Aur0101 is a drug-linker conjugate for ADC with potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the ADC linker MC-VC-PABC.
[1]. Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.
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