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- Geissoschizine methyl ether
Geissoschizine methyl ether
Geissoschizine methyl ether，一种 Uncaria hook 发现的生物碱类化合物，也是具有精神药物作用的 Yokukansan 的主要活性成分。Geissoschizine methyl ether 是有效的 5-HT1A 受体的激动剂。
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包装价格促销价数量
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1mg￥1850.001480.00- +
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5mg￥5537.004430.00- +
- 货号: ajcx14920
- CAS: 60314-89-8
- 别名: 缝籽木嗪甲醚
- 分子式: C22H26N2O3
- 分子量: 366.45
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C, protect from light
- 库存: 现货
Background
Geissoschizine methyl ether, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is potent 5-HT1A receptor agonist[1][2].
[1]. Matsumoto T, et al. In vitro identification of human cytochrome P450 isoforms involved in the metabolism of Geissoschizine methyl ether, an active component of the traditional Japanese medicine Yokukansan. Xenobiotica. 2016;46(4):325-34. [2]. Nishi A, et al. Geissoschizine methyl ether, an alkaloid in Uncaria hook, is a potent serotonin ?A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan. Neuroscience. 2012 Apr 5;207:124-36.
