A monoterpene
(+)-β-Citronellol is a monoterpene that has been found in Cannabis.1 It inhibits degranulation of cultured mast cells by 21.3% when used at a concentration of 0.5 mM.2 Unlike (R)-citronellal, it does not reduce the perceived bitterness of caffeine when used at a concentration of 5.9 nM.3 Formulations containing (+)-β-citronellol have been used as fragrance ingredients in various cosmetics, toiletries, and cleaning products.
1.Fletcher, R.S., and McKay, J.Industrial hemp cannabis cultivars and seeds with stable cannabinoid profiles(2006) 2.Kobayashi, Y., Sato, H., Yorita, M., et al.Inhibitory effects of geranium essential oil and its major component, citronellol, on degranulation and cytokine production by mast cellsBiosci. Biotechnol. Biochem.80(6)1172-1178(2016) 3.Suess, B., Brockhoff, A., Meyerhof, W., et al.The odorant (R)-citronellal attenuates caffeine bitterness by inhibiting the bitter receptors TAS2R43 and TAS2R46J. Agric. Food Chem.66(10)2301-2311(2018)
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