BMS-1001 hydrochloride

An inhibitor of the PD-1/PD-L1 interaction

原价

￥600-6300

价格

￥ 480-5040

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产品引用

Cell.Cell host & microbe.November 8, 2023
Cell . MOLECULAR PLANT . 1 February 2023
Cell . Immunity . August 10, 2021
Nature Communications.1413 (2022)
ACS . Nano Lett . April 10, 2023

BMS-1001 hydrochloride详情
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Background

BMS-1001 is a small molecule inhibitor of the interaction between programmed death protein 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) with an IC₅₀ value of 2.25 nM in a homogeneous time-resolved fluorescence (HTRF) binding assay.¹

1.Guzik, K., Zak, K.M., Grudnik, P., et al.Small-molecule inhibitors of the programmed cell death-1/programmed death-ligand 1 (PD-1/PD-L1) interaction via transiently induced protein states and dimerization of PD-L1J. Med. Chem.60(13)5857-5867(2017)

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生命科学

有机化学

无机化学

材料科学

BMS-1001 hydrochloride

BMS-1001 hydrochloride详情

Background