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- PKC (Protein kinase C)
- Phellopterin
Phellopterin
Phellopterin 是从 P. trifoliata 中分离得到的天然产物。Phellopterin 通过调节 Akt 和 PKC 通路降低 TNF-alpha 诱导的 VCAM-1 表达，从而抑制单核细胞与内皮细胞的粘附。
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包装价格促销价数量
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1mg￥1300.001040.00- +
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5mg￥2175.001740.00- +
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10mg￥3662.002930.00- +
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- 货号: ajcx15766
- CAS: 2543-94-4
- 别名: 珊瑚菜素
- 分子式: C17H16O5
- 分子量: 300.31
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
Phellopterin is a natural product isolated from P. trifoliata. Phellopterin reduce TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1].
[1]. Nizamutdinova IT, et al. Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells. Int Immunopharmacol. 2008 May;8(5):670-8.
