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D-I03 is a selective inhibitor of RAD52 with Kd of 25.8 ?M. D-I03 inhibits ssDNA annealing by RAD52 and D-loop formation with IC50 of 5 ?M and 8 ?M, respectively.
D-I03 is a selective inhibitor of RAD52 with Kd of 25.8 ?M. D-I03 inhibits ssDNA annealing by RAD52 and D-loop formation with IC50 of 5 ?M and 8 ?M, respectively.
[1] Fei Huang, et al. Nucleic Acids Res. 2016 May 19;44(9):4189-99.
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