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LCH-7749944

LCH-7749944 (GNF-PF-2356) is a novel and potent p21-activated kinase 4 (PAK4) inhibitor with an IC50 of 14.93 μM and has less potently inhibitory effect against PAK1, PAK5 and PAK6. LCH-7749944 causes successful inhibition of EGFR activity due to its inhi

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￥ 0-12480
LCH-7749944的二维码

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  • 库存: 现货
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  • 货号: ajcx16194
  • CAS: 796888-12-5
  • 别名: GNF-PF-2356
  • 分子式: C20H22N4O2
  • 分子量: 350.41
  • 纯度: >98%
  • 溶解度: DMSO: 250 mg/mL (713.45 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

LCH-7749944 (GNF-PF-2356) is a novel and potent p21-activated kinase 4 (PAK4) inhibitor with an IC50 of 14.93 μM and has less potently inhibitory effect against PAK1, PAK5 and PAK6. LCH-7749944 causes successful inhibition of EGFR activity due to its inhibitory effect on PAK4.


[1] Jian Zhang, et al. Cancer Lett. 2012 Apr 1;317(1):24-32.

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