Afoxolaner

An isoxazoline insecticide and acaricide

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
10mg

￥1025.00

820.00

- +
25mg

￥2025.00

1620.00

- +
50mg

￥3050.00

2440.00

- +
100mg

￥5112.00

4090.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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Background

Afoxolaner is an isoxazoline insecticide and acaricide.¹ It is a GABA receptor antagonist that inhibits GABA-induced currents in P. americana thoracic neurons (IC₅₀ = 10.8 nM). It induces mortality in 100% of C. felis after 24 and 48 hours when used at concentrations of 0.32 and 0.16 ?g/ml in an artificial membrane blood feeding device. Afoxolaner (2.5 mg/kg) eradicates C. felis infestation in dogs for up to 42 days and D. variabilis infestation for up to 30 days. Formulations containing afoxolaner have been used in the prevention of flea and tick infestations in dogs.

1.Shoop, W.L., Hartline, E.J., Gould, B.R., et al.Discovery and mode of action of afoxolaner, a new isoxazoline parasiticide for dogsVet. Parasitol.201(3-4)179-189(2014)