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  • Afoxolaner
Afoxolaner的可视化放大

Afoxolaner

An isoxazoline insecticide and acaricide

原价
¥1025-5112
价格
820-4090
Afoxolaner的二维码

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  • 库存: 现货
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  • 货号: ajcx16272
  • CAS: 1093861-60-9
  • 别名: 阿福拉纳
  • 分子式: C26H17ClF9N3O3
  • 分子量: 625.87
  • 纯度: >98%
  • 溶解度: DMSO: ≥ 250 mg/mL (399.44 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Afoxolaner is an isoxazoline insecticide and acaricide.1 It is a GABA receptor antagonist that inhibits GABA-induced currents in P. americana thoracic neurons (IC50 = 10.8 nM). It induces mortality in 100% of C. felis after 24 and 48 hours when used at concentrations of 0.32 and 0.16 ?g/ml in an artificial membrane blood feeding device. Afoxolaner (2.5 mg/kg) eradicates C. felis infestation in dogs for up to 42 days and D. variabilis infestation for up to 30 days. Formulations containing afoxolaner have been used in the prevention of flea and tick infestations in dogs.


1.Shoop, W.L., Hartline, E.J., Gould, B.R., et al.Discovery and mode of action of afoxolaner, a new isoxazoline parasiticide for dogsVet. Parasitol.201(3-4)179-189(2014)

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