G0507
G0507 是吡咯并嘧啶二酮化合物，一种有效的 LolCDE ABC 转运蛋白抑制剂。G0507 是大肠杆菌生长的抑制剂，并诱导胞浆外 σE 应激反应。G0507 用作解剖革兰氏阴性细菌中脂蛋白运输的化学探针。
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包装价格促销价数量
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5mg￥6475.005180.00- +
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10mg￥10800.008640.00- +
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50mg￥21375.0017100.00- +
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100mg￥32062.0025650.00- +
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- 货号: ajcx16304
- CAS: 1223998-29-5
- 别名:
- 分子式: C18H15N3O3S
- 分子量: 353.4
- 纯度: ＞98%
- 溶解度: DMSO: 5 mg/mL (14.15 mM)
- 储存: Store at -20°C
- 库存: 现货
Background
G0507, a pyrrolopyrimidinedione compound, is a potent LolCDE ABC Transporter inhibitor. G0507 is a inhibitor of Escherichia coli growth and induces the extracytoplasmic σE stress response. G0507 acts as a chemical probe to dissect lipoprotein trafficking in Gram-negative bacteria[1].
[1]. Nickerson NN, et al. A Novel Inhibitor of the LolCDE ABC Transporter Essential for Lipoprotein Trafficking in Gram-Negative Bacteria. Antimicrob Agents Chemother. 2018 Mar 27;62(4).
