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(5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) 是 Teprenone 的同分异构体,具有抗溃疡活性。(5E,9E,13E)-Teprenone 能诱导 HSP 基因的转录激活,可能导致应激条件下的胃粘膜防御提升。
(5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) is an isomer of Teprenone with antiulcer activity. (5E,9E,13E)-Teprenone induces transcriptional activation of HSP genes that may increase gastric mucosal defense at conditions of stress[1].
[1]. Hirakawa T, et al. Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa. Gastroenterology. 1996 Aug;111(2):345-57.
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