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- 2-Iminobiotin hydrobromide
2-Iminobiotin hydrobromide
2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) 是一种生物素 (维生素 H 或 B7) 类似物。2-Iminobiotin hydrobromide 是一种可逆的 NO 合酶抑制剂，作用于小鼠 iNOS 和大鼠 n-cNOS，Ki 值分别为 21.8 和 37.5 μM。2-Iminobiotin hydrobromide 与低温环境可保护人类神经细胞免受缺氧诱导的细胞损伤。
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包装价格促销价数量
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10mg￥1625.001300.00- +
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50mg￥4850.003880.00- +
- 货号: ajcx16426
- CAS: 76985-52-9
- 别名: 2-亚氨基生物素盐酸盐; Guanidinobiotin hydrobromide
- 分子式: C10H18BrN3O2S
- 分子量: 324.24
- 纯度: ＞98%
- 溶解度: DMSO: 125 mg/mL (385.52 mM)
- 储存: Store at -20°C
- 库存: 现货
Background
2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS, respectively[1]. 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage[2].
[1]. Sup SJ, et al. 2-Iminobiotin is an inhibitor of nitric oxide synthases. Biochem Biophys Res Commun. 1994 Oct 28;204(2):962-8. [2]. Zitta K, et al. 2-Iminobiotin Superimposed on Hypothermia Protects Human Neuronal Cells from Hypoxia-Induced Cell Damage: An in Vitro Study. Front Pharmacol. 2018 Jan 11;8:971.
