Selgantolimod (GS-9688) 是一种口服活性，有效和选择性的 Toll 样受体 8 (TLR8) 激动剂，用于治疗乙型肝炎病毒 (HBV) 和 HIV 感染。
Selgantolimod (GS-9688) is an orally active, potent and selective toll-like receptor 8 (TLR8) agonist for the treatment of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection[1][2][3].
[1]. Jules Levin. Efficacy and Safety of Oral TLR8 Agonist Selgantolimod in Virally Suppressed Adult Patients With Chronic Hepatitis B: a Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study. 2019 Nov 8-12. [2]. Benjamin Ryan. Selgantolimod Shows Promise as Treatment for Hepatitis B. November 18, 2019. [3]. Romas Geleziunas, et al. Modulators of toll-like receptors for the treatment of hiv. US20170071944A1.
动态评分
0.0