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  2. Reactive oxygen species (ROS)
  3. GFB-8438
  • GFB-8438
GFB-8438的可视化放大

GFB-8438

GFB-8438 is a novel, potent, and subtype selective TRP channel subfamily C (TRPC) inhibitor that is equipotent against TRPC4 and TRPC5 with IC50 of 0.18 μM and 0.29 μM, and shows excellent selectivity against TRPC6, other TRP family members , NaV 1.5, as

原价
￥1300-10575
价格
￥ 1040-8460
GFB-8438的二维码

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  • 库存: 现货
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  • 货号: ajcx16720
  • CAS: 2304549-73-1
  • 别名:
  • 分子式: C16H14ClF3N4O2
  • 分子量: 386.76
  • 纯度: >98%
  • 溶解度: DMSO: 83.33 mg/mL (215.46 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

GFB-8438 is a novel, potent, and subtype selective TRP channel subfamily C (TRPC) inhibitor that is equipotent against TRPC4 and TRPC5 with IC50 of 0.18 μM and 0.29 μM, and shows excellent selectivity against TRPC6, other TRP family members , NaV 1.5, as well as limited activity against the hERG channel.


[1] Maolin Yu, et al. ACS Med Chem Lett. 2019 Oct 22;10(11):1579-1585.

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