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- Cyclooxygenase (COX)
- Isoxicam
Isoxicam
Isoxicam 是一种口服有效的非甾体抗炎剂，可用于关节炎的研究。Isoxicam 是一种非选择性的 COX-1 和 COX-2 抑制剂。
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包装价格促销价数量
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100mg￥625.00500.00- +
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250mg￥1187.00950.00- +
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- 货号: ajcx16808
- CAS: 34552-84-6
- 别名: 伊索昔康
- 分子式: C14H13N3O5S
- 分子量: 335.34
- 纯度: ＞98%
- 溶解度: DMSO: 5 mg/mL (14.91 mM)
- 储存: Store at -20°C
- 库存: 现货
Background
Isoxicam is an orally active, long-acting, non-steroidal anti-inflammatory agent for the research of arthritis[1]. Isoxicam is a nonselective inhibitor of COX-1 and COX-2[2].
[1]. DiPasquale G, et al. The antiinflammatory properties of isoxicam (4-hydroxy-2methyl-N-(5-methyl-3isoxolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide). Agents Actions. 1975 Aug;5(3):256-63. [2]. Xu S, et al. Oxicams bind in a novel mode to the cyclooxygenase active site via a two-water-mediated H-bonding Network. J Biol Chem. 2014 Mar 7;289(10):6799-808.
