PF-06952229
PF-06952229 是一种强效、选择性和口服的 TGFbR1 抑制剂。PF-06952229 与 TGFbR1 特异性结合，阻止 TGFbR1 介导的信号转导。PF-06952229 是一种很有前途的抗肿瘤试剂 (antineoplastic agent)，主要用于研究实体瘤，尤其是转移性乳腺癌。
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
-
包装价格促销价数量
-
5mg￥3775.003020.00- +
-
10mg￥6475.005180.00- +
-
50mg￥18700.0014960.00- +
-
100mg￥29925.0023940.00- +
已选
0
种
0
瓶
金额:
￥0.00
首页
收藏
- 货号: ajcx17008
- CAS: 1801333-55-0
- 别名:
- 分子式: C23H24ClFN4O3
- 分子量: 458.91
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
PF-06952229 is a potent, selective and orally active TGFbR1 inhibitor. PF-06952229 specifically binds to TGFbR1 and prevents TGFbR1-mediated signal transduction. PF-06952229 is a promising antineoplastic agent for the study solid tumors, especifically metastatic breast cancer[1].
[1]. Flavia Mercer Pernasetti, et al. Combinations of tgfb inhibitors and cdk inhibitors for the treatment of breast cancer. Patent WO2020058820A1.
