GPLGIAGQ TFA

GPLGIAGQ TFA 是一种 MMP2 可切割的多肽，在脂质体和胶束纳米载体中都被用作刺激敏感的连接物，用于 MMP2 触发的肿瘤靶向治疗。GPLGIAGQ TFA可用于合成光动力治疗 (PDT) 中独特的 MMP2 靶向光敏剂。

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库存: 现货

可选规格

包装

价格

促销价

数量
5mg

￥1100.00

880.00

- +
10mg

￥1625.00

1300.00

- +
50mg

￥3775.00

3020.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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货号: ajcx17016
CAS: N/A
别名:
分子式: C33H54F3N9O12
分子量: 825.83
纯度: >98%
溶解度: Soluble in DMSO
储存: Store at -20°C,Sealed storage, away from moisture
库存: 现货

Background

GPLGIAGQ TFA, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ TFA can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT)[1][2][3].

[1]. Hou W, et al. MMP2-Targeting and Redox-Responsive PEGylated Chlorin e6 Nanoparticles for Cancer Near-Infrared Imaging and Photodynamic Therapy. ACS Appl Mater Interfaces. 2016 Jan 20;8(2):1447-57. [2]. Zhu L, et al. Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs. Biomaterials. 2014 Apr;35(13):4213-22. [3]. Liu FH, et al. Enzyme-sensitive cytotoxic peptide-dendrimer conjugates enhance cell apoptosis and deep tumor penetration. Biomater Sci. 2018 Feb 27;6(3):604-613.