Background:
(±)17(18)-EpETE is biosynthesized by the stereospecific epoxidation of the ω-3 bond of EPA. (±)17(18)-EpETE at 100 nM was found to be a potent and selective activator of BK-type calcium activated potassium ion channels in vascular smooth muscle cells. It is possible that some of the physiologic effects of fish oil-enhanced diets could be due to this epoxygenase metabolite. (±)17(18)-EpETE MaxSpec® standard is a quantitative grade standard of (±)17(18)-EpETE that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This (±)17(18)-EpETE MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
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