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A caspase-3 inhibitor
Ac-AAVALLPAVLLALLAP-DEVD-CHO is a composite of Ac-DEVD-CHO , a peptide inhibitor of caspase-3 and -7, and a cell-permeable hydrophobic sequence derived from K-FGF. It is an inhibitor of caspase-3 that reduces caspase-3 activity and apoptosis induced by prostaglandin E2 in rat cortical neurons when used at concentrations ranging from 1 to 2.5 μM.
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