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  • Amyloid-β Precursor Protein (96-110) Peptide (cyclized) (human) (trifluoroacetate salt)
Amyloid-β Precursor Protein (96-110) Peptide (cyclized) (human) (trifluoroacetate salt)的可视化放大

Amyloid-β Precursor Protein (96-110) Peptide (cyclized) (human) (trifluoroacetate salt)

A 15-residue cyclized APP fragment

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Amyloid-β Precursor Protein (96-110) Peptide (cyclized) (human) (trifluoroacetate salt)的二维码
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  • 货号: ajcx17470
  • CAS: N/A
  • 别名: Cyclized APP (96-110), Cyclized APP96-110
  • 分子式: C81H128N32O19S2 ? XCF3COOH
  • 分子量: 1918.2
  • 纯度: >98%
  • 溶解度: Water: 1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Amyloid-β precursor protein (96-110) peptide (cyclized) is a synthetic peptide consisting of amino acids 96-110 of amyloid precursor peptide (APP) that is cyclized via a bridge between the cysteine residues at positions 3 and 10. It is homologous to the heparin-binding domain of human APP and inhibits binding of [125I]APP to heparin in vitro with an IC50 value of approximately 100 nM. Amyloid-β precursor protein (96-110) peptide (cyclized) inhibits neurite outgrowth induced by APP and mouse postnatal heparan sulfate proteoglycans (HSPG) in primary mouse hippocampal neurons when used at a concentration of 10 μg/ml.

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