安捷凯在线客服
- 客服:
- 电话: 13061953619
- 微信:
A peptide agonist of PAR4
PAR4 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4) and an amide form of PAR4 (1-6) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence. It induces aggregation of rat platelets with an EC50 value of 40 μM. PAR4 (1-6) amide (100 μM) induces smooth muscle relaxation and prostaglandin E2 release in isolated mouse tracheal segments, effects that are inhibited by indomethacin .
动态评分
0.0