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A structural analog of PGI2
5-cis-15(R)-Iloprost is the C-5 cis-isomer and 15(R)-epimer of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin. There are no published studies of the pharmacological properties of 5-cis-15(R)-iloprost.
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